PLEURAL EFFUSION ASSOCIATED WITH FELINE INFECTIOUS PERITONITIS IN A KITTEN: MOLECULAR AND HISTOPATHOLOGICAL INVESTIGATION
DOI:
https://doi.org/10.71336/jabs.936Keywords:
Feline infectious peritonitis,, molecular and histopathological examination,, pleural effusion,Abstract
This study was aimed at investigating the molecular typing of coronavirus and histopathological findings of the lungs in a kitten with feline infectious peritonitis. A stray kitten, which was in respiratory distress and had not responded to a one-week course of antibiotic treatment, was referred to the Animal Hospital of Faculty of Veterinary Medicine at Atatürk University. In the physical examination, acute respiratory failure developed and did not respond emergency therapeutic intervention. Molecular and histopathological examinations were performed. Feline coronavirus type I was determined by sequence analysis of the lung and pleural fluid samples. Macroscopic findings revealed hemorrhagic fluid in the chest cavity. Fibrinoid necrosis, desquamation, edema and lymphoplasmacytic cell infiltrations were observed in the histopathological examination of the lungs. Thus, feline coronavirus type I was determined to cause severe lesions with edema, necrosis and lymphoplasmacytic cell infiltrations in the lungs and respiratory distress.
References
Pedersen, N. C. (2009): A review of feline infectious peritonitis virus infection: 1963-2008. Journal of Feline Medicine and Surgery 11: 225-258. DOI: https://doi.org/10.1016/j.jfms.2008.09.008
Addie, D. D., Jarrett, J. O. (2001): Use of a reverse-transcriptase polymerase chain reaction for monitoring feline coronavirus shedding by healthy cats. Veterinary Record 148: 649-653. DOI: https://doi.org/10.1136/vr.148.21.649
Kipar, A., Meli, M.L. (2014): Feline infectious peritonitis: still an enigma? Veterinary Pathology 51: 505-526. DOI: https://doi.org/10.1177/0300985814522077
Amer, A., Siti-Suri, A., Mohd, H-B., Abdul-Rahman, O., Ibrahim, T., Azmi, T., Faruku, B., Ajwad, A. (2012): Molecular and pathological identification of feline coronavirus type I. African Journal of Biotechnology 11: 10451-10461.
Tekes, G., Thiel, H. J. (2016): Feline coronaviruses. Advances in Virus Research 96: 193-218. DOI: https://doi.org/10.1016/bs.aivir.2016.08.002
Pedersen, N. C., Boyle, J. F., Floyd, K., Fudge, A., Barker, J. (1981). An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis. American Journal of Veterinary Research 42: 368-377. DOI: https://doi.org/10.2460/ajvr.1981.42.03.368
Simons, F. A., Vennema, H., Rofina, J. E., Pol, J. M., Horzinek, M. C., Rottier, P. J. M. (2005): A mRNA PCR for the diagnosis of feline infectious peritonitis. Journal of Virological Methods 124: 111-116. DOI: https://doi.org/10.1016/j.jviromet.2004.11.012
O'Reilly, K. J., Fishman, B., Hitchcock, L. M. (1979): Feline infectious peritonitis: isolation of a coronavirus. Veterinary Record 104: 348. DOI: https://doi.org/10.1136/vr.104.15.348
Gonzalez, J. M, Gomez-Puertas, P., Cavanagh, D., Gorbalenya, A. E., Enjuanes, L. (2003): A comparative sequence analysis to revise the current taxonomy of the family Coronaviridae. Archives of Virology 148: 2207-2235. DOI: https://doi.org/10.1007/s00705-003-0162-1
Benetka, V., Kubber-Heiss, A., Kolodziejek, J., Nowotny, N., Hofmann-Parisot, M., Mostl, K. (2004): Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis. Veterinary Microbiology 99: 31-42. DOI: https://doi.org/10.1016/j.vetmic.2003.07.010
Takano, T., Ohyama, T., Kokumoto, A., Satoh, R., Hohdatsu, T. (2011): Vascular endothelial growth factor (VEGF), produced by feline infectious peritonitis (FIP) virus-infected monocytes and macrophages, induces vascular permeability and effusion in cats with FIP. Virus Research 158: 161-168. DOI: https://doi.org/10.1016/j.virusres.2011.03.027
Takano, T., Azuma, N., Satoh, M., Toda, A., Hashida, Y., Satoh, R., Hohdatsu, T. (2009): Neutrophil survival factors (TNF-alpha, GM-CSF, and G-CSF) produced by macrophages in cats infected with feline infectious peritonitis virus contribute to the pathogenesis of granulomatous lesions. Archives of Virology 154: 775-781. DOI: https://doi.org/10.1007/s00705-009-0371-3
Hartmann K, Binder C, Hirschberger J, Cole D, Reinacher M, Schroo S (2003): Comparison of different tests to diagnose feline infectious peritonitis. Journal of Veterinary Internal Medicine 17(6): 781-790. DOI: https://doi.org/10.1111/j.1939-1676.2003.tb02515.x
Riemer, F., Kuehner, K. A., Ritz, S., Sauter-Louis, C., Hartmann, K. (2016): Clinical and laboratory features of cats with feline infectious peritonitis--a retrospective study of 231 confirmed cases (2000-2010). Journal of Feline Medicine and Surgery 18: 348-356. DOI: https://doi.org/10.1177/1098612X15586209
Pedersen, N. C. (2014): An update on feline infectious peritonitis: diagnostics and therapeutics. Veterinary Journal 201: 133-141. DOI: https://doi.org/10.1016/j.tvjl.2014.04.016
Baydar, E., Eröksüz, Y., Timurkan, M. Ö., Eröksüz, H. (2014): Feline infectious peritonitis with distinct ocular involvement in a cat in Turkey. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 20: 961-965. DOI: https://doi.org/10.9775/kvfd.2014.11195
Hall, T. A. (1999): BioEdit: A user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symposium Series 41: 95–98.
Tamura, K., Stecher, G., Peterson, D., Filipski, A., Kumar, S. (2013): MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Molecular Biology and Evolution 30: 2725-2729. DOI: https://doi.org/10.1093/molbev/mst197
Tsai, H. Y., Chueh, L. L., Lin, C. N., Su, B. L. (2011): Clinicopathological findings and disease staging of feline infectious peritonitis: 51 cases from 2003 to 2009 in Taiwan. Journal of Feline Medicine and Surgery 13: 74-80. DOI: https://doi.org/10.1016/j.jfms.2010.09.014
Norris, J. M., Bosward, K. L., White, J. D., Baral, R. M., Catt, M. J., Malik, R. (2005): Clinicopathological findings associated with feline infectious peritonitis in Sydney, Australia: 42 cases (1990-2002). Australian Veterinary Journal 83:666-673. DOI: https://doi.org/10.1111/j.1751-0813.2005.tb13044.x
Oğuzoğlu, T. Ç., Muz, D., Timurkan, M. Ö., Maral, N., Gurcan, I. S. (2013): Prevalences of feline coronavirus (FCoV), feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV) and feline parvovirus (FPV) among domestic cats in Ankara, Turkey. Revue De Médecine Véterinaire 164: 511-516.
Beatty, J., Barrs, V. (2010): Pleural effusion in the cat: a practical approach to determining aetiology. Journal of Feline Medicine and Surgery 12: 693-707. DOI: https://doi.org/10.1016/j.jfms.2010.07.013
Konig, A., Hartmann, K., Mueller, R. S., Wess, G., Schulz, B. S. (2018): Retrospective analysis of pleural effusion in cats. Journal of Feline Medicine and Surgery 21(12): 1102-1110. DOI: https://doi.org/10.1177/1098612X18816489
Ruiz, M. D., Vessieres, F., Ragetly, G. R., Hernandez, J. L. (2018): Characterization of and factors associated with causes of pleural effusion in cats. Journal of the American Veterinary Medical Association 253: 181-187. DOI: https://doi.org/10.2460/javma.253.2.181
Doenges, S. J., Weber, K., Dorsch, R., Fux, R., Hartmann, K. (2017): Comparison of real-time reverse transcriptase polymerase chain reaction of peripheral blood mononuclear cells, serum and cell-free body cavity effusion for the diagnosis of feline infectious peritonitis. Journal of Feline Medicine and Surgery 19: 344-350. DOI: https://doi.org/10.1177/1098612X15625354
Hohdatsu, T., Okada, S., Ishizuka, Y., Yamada, H., Koyama, H. (1992): The prevalence of types I and II feline coronavirus infections in cats. The Journal of Veterinary Medical Science 54: 557-562. DOI: https://doi.org/10.1292/jvms.54.557
Kummrow, M., Meli, M. L., Haessig, M., Goenczi, E., Poland, A., Pedersen, N. C., Hofmann-Lehmann, R., Lutz, H. (2005): Feline coronavirus serotypes 1 and 2: seroprevalence and association with disease in Switzerland. Clinical and Diagnostic Laboratory Immunology 12: 1209-1215. DOI: https://doi.org/10.1128/CDLI.12.10.1209-1215.2005
Lin, C. N., Su, B. L., Wang, C. H., Hsieh, M. W., Chueh, T. J., Chueh, L. L. (2009): Genetic diversity and correlation with feline infectious peritonitis of feline coronavirus type I and II: a 5-year study in Taiwan. Veterinary Microbiology 136: 233-239. DOI: https://doi.org/10.1016/j.vetmic.2008.11.010
Li, C., Liu, Q., Kong, F., Guo, D., Zhai, J., Su, M., Sun, D. (2019): Circulation and genetic diversity of feline coronavirus type I and II from clinically healthy and FIP-suspected cats in China. Transboundary and Emerging Diseases 66: 763-775. DOI: https://doi.org/10.1111/tbed.13081
Shiba, N., Maeda, K., Kato, H., Mochizuki, M., Iwata, H. (2007): Differentiation of feline coronavirus type I and II infections by virus neutralization test. Veterinary Microbiology 124, 348-352. DOI: https://doi.org/10.1016/j.vetmic.2007.04.031
Kipar, A., Baptiste, K., Barth, A., Reinacher, M. (2006): Natural FCoV infection: cats with FIP exhibit significantly higher viral loads than healthy infected cats. Journal of Feline Medicine and Surgery 8: 69-72. DOI: https://doi.org/10.1016/j.jfms.2005.07.002
Kipar, A., Bellmann, S., Kremendahl, J., Kohler, K., Reinacher, M. (1998): Cellular composition, coronavirus antigen expression and production of specific antibodies in lesions in feline infectious peritonitis. Veterinary Immunology and Immunopathology 65: 243-257. DOI: https://doi.org/10.1016/S0165-2427(98)00158-5
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